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ORAL MACROMOLECULE DELIVERY

Permeation Enhancement
Targeted Delivery
Gastric Protection

Oral Macromolecule Delivery

Today, most macromolecules are delivered in traditional invasive injectable formats, which often results in poor patient compliance and are therefore not the most suitable route for long-term treatment. Although oral delivery remains the preferred route for developers of new therapies, it poses a variety of development challenges to formulation scientists, for example:

  • Poor absorption due to rigid molecular geometry and flexibility
  • Permeation limitations caused by tight cell junctions and limited transcellular pathways
  • Low stability, because of proteolytic enzymes of the stomach and lumen, as well as harsh acidic gastric conditions

最新色情影片 OptiGel庐 Bio technology incorporates a proprietary technology that may overcome the traditional hurdles by enhancing permeability and enabling a targeted delivery through enteric coating.

Our industry leading Zydis庐 ODT technology enables fast dissolve formulations of large molecule allergens, viral vaccines, and peptides via sub-lingual delivery.

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